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Illumina, Inc.
Quest Diagnostics Incorporated
KURABO INDUSTRIES LTD
PerkinElmer chemagen Technologie GmbH
Biodesix
Guardant Health
QIAGEN
Sequenom, Inc.
Agilent Technologies, Inc.
Fluxion Biosciences Inc.
Natera, Inc.
Agena Bioscience, Inc.
Paragon Genomics, Inc.
Lucence Health Inc.
Eurofins Genomics
Thermo Fisher Scientific
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Circulating Cell-Free Tumor DNA Market is estimated to be valued at USD 9.22 Bn in 2025 and is expected to reach USD 39.05 Bn by 2032, growing at a compound annual growth rate (CAGR) of 22.9% from 2025 to 2032.
Report Coverage
Report Details
Base Year:
2024
Market Size in 2025:
USD 9.22 Bn
Historical Data for:
2020 To 2024
Forecast Period:
2025 To 2032
Forecast Period 2025 to 2032 CAGR:
22.90%
2032 Value Projection:
USD 39.05 Bn
The term circulating tumor DNA (ctDNA) refers to DNA from malignant cells and tumors that circulate in the bloodstream. The nucleus of a cell contains most of the DNA. Cells die and are replaced by new ones as a tumor expands. The broken-down dead cells discharge their contents, including DNA, into the bloodstream. ctDNA are short segments of DNA that are typically less than 200 nucleotides in length. The amount of ctDNA varies from person to person and is influenced by the type of tumor, its location, and, in the case of malignant tumors, the stage of the disease. Circulating tumor DNA (ctDNA) usually contains genetic changes that could be useful for detecting cancer. Other significant uses of ctDNA include prognosis, therapeutic monitoring, and tumor volume estimation. When new cancer detection tests can spot cancer in its earliest, asymptomatic stage, when cure rates are highest, they have the greatest clinical utility. Circulating tumor DNA analysis can help in the early detection of cancer and is also used in providing molecular targeting therapeutics.
Market Dynamics
Increasing adoption of organic growth strategies, such as product launches by key players in the market to expand their product portfolio, is expected to drive market growth over the forecast period. For instance, in July 2022, BillionToOne Inc., a next-generation molecular diagnostics company, announced the launch of its first oncology liquid biopsy products, Northstar Select and Northstar Response. The products are currently available for research use with select academic cancer centers. Northstar Select is a comprehensive pan-cancer somatic mutation profiling panel. Leveraging BillionToOne's proprietary molecular counting technology, or Quantitative Counting Templates (QCTs), the panel achieves a notable limit of detection for the identification of actionable alterations. Meanwhile, Northstar Response is a methylation-based, tissue-agnostic treatment response monitoring assay.
Key features of the study:
This report provides an in-depth analysis of the global circulating cell-free tumor DNA market, and provides market size (US$ Billion) and Compound Annual Growth Rate (CAGR%) for the forecast period 2025-2032, considering 2024 as the base year
It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by key players
It profiles key players in the global circulating cell-free tumor DNA market based on the following parameters - company highlights, products portfolio, key highlights, financial performance, and strategies
Key companies covered as a part of this study are Biocept, Inc., Illumina, Inc., Quest Diagnostics Incorporated, KURABO INDUSTRIES LTD, PerkinElmer chemagen Technologie GmbH, Biodesix, Guardant Health, QIAGEN, Sequenom, Inc., Agilent Technologies, Inc., Fluxion Biosciences Inc., Natera, Inc., Agena Bioscience, Inc., Paragon Genomics, Inc., Lucence Health Inc., Eurofins Genomics, Thermo Fisher Scientific.
Insights from this report will allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
The global circulating cell-free tumor DNA analysis report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global circulating cell-free tumor DNA market
Detailed Segmentation:
Global Circulating Cell-Free Tumor DNA Market, By Tumor Type:
Malignant Tumors
Precancerous Tumors
Global Circulating Cell-Free Tumor DNA Market, By Cancer Type:
Lung Cancer
Colorectal Cancer
Breast Cancer
Others
Global Circulating Cell-Free Tumor DNA Market, By Technology:
PCR
Massively Parallel Sequencing
Single Nucleotide Polymorphism
Global Circulating Cell-Free Tumor DNA Market, By Application:
Cancer Diagnosis
Targeting Therapeutics
Prognosis Indication
Global Circulating Cell-Free Tumor DNA Market, By Region:
North America
U.S.
Canada
Latin America
Brazil
Mexico
Argentina
Rest of Latin America
Europe
Germany
U.K.
France
Italy
Spain
Russia
Rest of Europe
Asia Pacific
China
India
Japan
Australia
South Korea
ASEAN
Rest of Asia Pacific
Middle East
GCC
Israel
Rest of Middle East
Africa
South Africa
Central Africa
North Africa
Company Profiles
Biocept, Inc.
Illumina, Inc.
Quest Diagnostics Incorporated
KURABO INDUSTRIES LTD
PerkinElmer chemagen Technologie GmbH
Biodesix
Guardant Health
QIAGEN
Sequenom, Inc.
Agilent Technologies, Inc.
Fluxion Biosciences Inc.
Natera, Inc.
Agena Bioscience, Inc.
Paragon Genomics, Inc.
Lucence Health Inc.
Eurofins Genomics
Thermo Fisher Scientific
Table of Contents
1. Research Objectives and Assumptions
Research Objectives
Assumptions
Abbreviations
2. Market Purview
Report Description
Market Definition and Scope
Executive Summary
Market Snapshot, By Tumor Type
Market Snapshot, By Cancer Type
Market Snapshot, By Technology
Market Snapshot, By Application
Market Snapshot, By Region
Coherent Opportunity Map (COM)
3. Market Dynamics, Regulations, and Trends Analysis
Market Dynamics
Drivers
Restraints
Market Opportunities
Impact Analysis
Key Highlights
Product Launch
Technological Advancements
PEST Analysis
Regulatory Scenario
Mergers and Acquisitions
4. Global Circulating Cell-free Tumor DNA Market- COVID-19 Impact Analysis
Economic Impact
COVID-19 Epidemiology
Impact on Supply and Demand
5. Global Circulating Cell-free Tumor DNA Market, By Tumor Type, 2020 - 2032, (US$ Billion)
Introduction
Market Share Analysis, 2025 and 2032 (%)
Y-o-Y Growth Analysis, 2021 - 2032
Segment Trends
Malignant Tumors
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Billion)
Precancerous Tumors
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Billion)
6. Global Circulating Cell-free Tumor DNA Market, By Cancer Type, 2020 - 2032, (US$ Billion)
Introduction
Market Share Analysis, 2025 and 2032 (%)
Y-o-Y Growth Analysis, 2021 - 2032
Segments Trends
Lung Cancer
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Billion)
Colorectal Cancer
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Billion)
Breast Cancer
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Billion)
Others
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Billion)
7. Global Circulating Cell-free Tumor DNA Market, By Technology, 2020 - 2032, (US$ Billion)
Introduction
Market Share Analysis, 2025 and 2032 (%)
Y-o-Y Growth Analysis, 2021 - 2032
Segments Trends
PCR
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Billion)
Massively Parallel Sequencing
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Billion)
Single Nucleotide Polymorphism
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Billion)
8. Global Circulating Cell-free Tumor DNA Market, By Application, 2020 - 2032, (US$ Billion)
Introduction
Market Share Analysis, 2025 and 2032 (%)
Y-o-Y Growth Analysis, 2021 - 2032
Segment Trends
Cancer Diagnosis
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Billion)
Targeting Therapeutics
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Billion)
Prognosis Indication
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Billion)
9. Global Circulating Cell-free Tumor DNA Market, By Region, 2020 - 2032, (US$ Billion)
Introduction
Market Share Analysis, By Region, 2025 and 2032 (%)
Y-o-Y Growth Analysis, For Regions, 2021-2032
Regional Trends
North America
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Tumor Type, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Cancer Type, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Technology, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Application, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2020 - 2032, (US$ Billion)
U.S.
Canada
Latin America
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Tumor Type, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Cancer Type, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Technology, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Application, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2020 - 2032, (US$ Billion)
Brazil
Mexico
Argentina
Rest of Latin America
Europe
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Tumor Type, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Cancer Type, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Technology, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Application, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2020 - 2032, (US$ Billion)
U.K.
Germany
Italy
France
Spain
Russia
Rest of Europe
Asia Pacific
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Tumor Type, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Cancer Type, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Technology, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Application, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2020 - 2032, (US$ Billion)
China
India
Japan
ASEAN
Australia
South Korea
Rest of Asia Pacific
Middle East
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Tumor Type, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Cancer Type, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Technology, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Application, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2020 - 2032, (US$ Billion)
GCC
Israel
Rest of Middle East
Africa
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Tumor Type, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Cancer Type, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Technology, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Application, 2020 - 2032, (US$ Billion)
Market Size and Forecast, and Y-o-Y Growth, By Country/Region, 2020 - 2032, (US$ Billion)