Global G-Protein Coupled Receptors Market is estimated to be valued at USD 5.73 Bn in 2025 and is expected to reach USD 9.76 Bn by 2032, growing at a compound annual growth rate (CAGR) of 7.9% from 2025 to 2032.
Report Coverage
Report Details
Base Year:
2024
Market Size in 2025:
USD 5.73 Bn
Historical Data for:
2020 To 2024
Forecast Period:
2025 To 2032
Forecast Period 2025 to 2032 CAGR:
7.90%
2032 Value Projection:
USD 9.76 Bn
Figure. Global G-Protein Coupled Receptors Market Share (%), By Region 2025
G-protein coupled receptors (GPCRs) constitute a prominent and diverse family of cell surface receptors that play pivotal roles in cellular signaling and communication. These receptors are integral membrane proteins characterized by their distinct structural features, including seven transmembrane helices, an extracellular N-terminus, and an intracellular C-terminus. The seven transmembrane domains create a characteristic structure often likened to a bundle of alpha helices, facilitating the receptor's insertion into the cell membrane. The activation of GPCRs is triggered by the binding of specific ligands, which can include hormones, neurotransmitters, and other signaling molecules. Ligand binding induces conformational changes in the receptor, leading to its activation. The ligand-binding site is typically located at the extracellular N-terminus of the receptor, and the binding event initiates a cascade of intracellular signaling events. One of the hallmark features of GPCRs is their interaction with G-proteins, which are heterotrimeric complexes consisting of alpha, beta, and gamma subunits. Upon activation of the GPCR, the receptor undergoes conformational changes that allow it to catalyze the exchange of GDP for GTP on the alpha subunit of the G-protein. This activation of the G-protein triggers downstream signaling pathways, influencing various cellular responses.
Market Dynamics:
The G-protein coupled receptors (GPCR) market is driven by rising incidence of chronic diseases such as cancer and cardiovascular diseases globally. GPCRs play a key role in these conditions and are actively pursued as drug targets. Furthermore, increasing pharmaceutical research and development (R&D) expenditures, availability of advanced screening technologies for GPCR drug discovery, and growing clinical pipeline of GPCR-targeted candidates are fueling market opportunities. However, high costs that are associated with GPCR drug development and commercialization hamper faster market growth. Complex signaling pathways downstream of GPCR activation also pose challenges. Industry players are investing in overcoming technical roadblocks to fully leverage potential of GPCRs as therapeutic targets
Key features of the study:
This report provides in-depth analysis of the global G-protein coupled receptors market, and provides market size (US$ Bn) and compound annual growth rate (CAGR %) for the forecast period (2025-2032), considering 2024 as the base year
It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by key players
It profiles key players in the global G-protein coupled receptors market based on the following parameters - company highlights, products portfolio, key highlights, financial performance, and strategies
Key companies covered as a part of this study Thermo Fisher Scientific Inc., Eurofins Scientific, QIAGEN, WuXi AppTec, Promega Corporation, Abcam plc, Merck KGaA, PerkinElmer Inc., Enzo Biochem Inc., and BD.
Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
Global G-protein coupled receptors market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global G-protein coupled receptors market
Detailed Segmentation:
Global G-Protein Coupled Receptors Market, By Product
Cell Lines
Detection Kits
Cell Culture Reagents
Ligands
Global G-Protein Coupled Receptors Market, By Assay Type
cAMP Functional Assays
Calcium Functional Assays
B-Arrestin Functional Assays
Radioligand Binding & GTPYS Functional Assays
Internalization Assays
Trafficking Assays
Other Assays
Global G-Protein Coupled Receptors Market, By Application
Cancer Research
CNS Research
Metabolic Research
Cardiovascular Research
Respiratory Research
Inflammation Research
Other Applications
Global G-Protein Coupled Receptors Market, By Region
North America
Europe
Asia Pacific
Latin America
Middle East
Africa
Company Profiles
Thermo Fisher Scientific Inc.
Eurofins Scientific
QIAGEN
WuXi AppTec
Promega Corporation
Abcam plc
Merck KGaA
PerkinElmer Inc.
Enzo Biochem Inc.,
Table of Contents
1. Research Objectives and Assumptions
Research Objectives
Assumptions
Abbreviations
2. Market Purview
Report Description
Market Definition and Scope
Executive Summary
Global G-Protein Coupled Receptors Market, By Product
Global G-Protein Coupled Receptors Market, By Assay Type
Global G-Protein Coupled Receptors Market, By Application
Global G-Protein Coupled Receptors Market, By Region
Coherent Opportunity Map (COM)
3. Market Dynamics, Regulations, and Trends Analysis
Market Dynamics
Increasing R&D investment by pharmaceutical companies
Increasing prevalence of chronic diseases
Technological advancements in GPCR assays
Key Highlights
Regulatory Scenario
Recent Trends
PEST Analysis
PORTER's Analysis
Mergers, Acquisitions, and Collaborations
4. Global G-Protein Coupled Receptors Market- Impact of Coronavirus (COVID-19) Pandemic
COVID-19 Epidemiology
Supply Side and Demand Side Analysis
Economic Impact
5. Global G-Protein Coupled Receptors Market, By Product, 2020-2032, (US$ Bn)
Introduction
Market Share Analysis, 2025 and 2032 (%)
Y-o-Y Growth Analysis, 2021 - 2032
Segment Trends
Cell Lines
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032,(US$ Bn)
Detection Kits
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032,(US$ Bn)
Cell Culture Reagents
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032,(US$ Bn)
Ligands
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032,(US$ Bn)
6. Global G-Protein Coupled Receptors Market, By Assay Type, 2020-2032, (US$ Bn)
Introduction
Market Share Analysis, 2025 and 2032 (%)
Y-o-Y Growth Analysis, 2021 - 2032
Segment Trends
cAMP Functional Assays
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032,(US$ Bn)
Calcium Functional Assays
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032,(US$ Bn)
B-Arrestin Functional Assays
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032,(US$ Bn)
Radioligand Binding & GTPYS Functional Assays
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032,(US$ Bn)
Internalization Assays
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032,(US$ Bn)
Trafficking Assays
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032,(US$ Bn)
Other Assays
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032,(US$ Bn)
7. Global G-Protein Coupled Receptors Market, By Application, 2020-2032, (US$ Bn)
Introduction
Market Share Analysis, 2025 and 2032 (%)
Y-o-Y Growth Analysis, 2021 - 2032
Segment Trends
Cancer Research
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032,(US$ Bn)
CNS Research
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032,(US$ Bn)
Metabolic Research
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032,(US$ Bn)
Cardiovascular Research
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032,(US$ Bn)
Respiratory Research
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032,(US$ Bn)
Inflammation Research
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032,(US$ Bn)
Other Applications
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032,(US$ Bn)
8. Global G-Protein Coupled Receptors Market, By Region, 2020-2032, (US$ Bn)
Introduction
Market Share Analysis, By Region, 2025 and 2032 (%)
Y-o-Y Growth Analysis, For Region, 2021 -2032
Country Trends
North America
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Product, 2020-2032,(US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Assay Type, 2020-2032,(US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Application, 2020-2032,(US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2020-2032,(US$ Bn)
U.S.
Canada
Europe
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Product, 2020-2032,(US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Assay Type, 2020-2032,(US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Application, 2020-2032,(US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2020-2032,(US$ Bn)
Germany
U.K.
Spain
France
Italy
Russia
Rest of Europe
Asia Pacific
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Product, 2020-2032,(US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Assay Type, 2020-2032,(US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Application, 2020-2032,(US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2020-2032,(US$ Bn)
China
India
Japan
Australia
South Korea
ASEAN
Rest of Asia Pacific
Latin America
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Product, 2020-2032,(US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Assay Type, 2020-2032,(US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Application, 2020-2032,(US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2020-2032,(US$ Bn)
Brazil
Argentina
Mexico
Rest of Latin America
Middle East
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Product, 2020-2032,(US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Assay Type, 2020-2032,(US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Application, 2020-2032,(US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2020-2032,(US$ Bn)
GCC Countries
Israel
Rest of Middle East
Africa
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Product, 2020-2032,(US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Assay Type, 2020-2032,(US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Application, 2020-2032,(US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Country/Region, 2020-2032,(US$ Bn)