단백질 시퀀싱은 단백질의 아미노산의 정확한 순서를 결정하는 과정이며, 단백질의 구조, 기능 및 생체 시스템에서의 역할을 이해하는데 매우 중요합니다.
생명 공학, 생물 의학 연구, 의약품 및 질병 진단과 같은 분야에서 중요한 역할을 수행하고 있습니다. 단백질 시퀀스를 통해 번역 후 변형, 단백질 상호작용, 질환 메커니즘에 대한 귀중한 통찰을 얻을 수 있으며 정밀 의료 및 표적 치료의 진보가 가능합니다.
단백질 시퀀싱의 두 가지 주요 기술은 에드만 분해와 질량 분석입니다. 에드만 분해는 작은 단백질에 사용되며 아미노산을 순차적으로 제거합니다. 한편, 질량 분석은 높은 처리량과 복잡한 샘플의 분석 능력으로 인해 대규모 단백질체학에 널리 사용됩니다. 또한 이 시장은 장비, 시약, 시퀀싱 프로세스를 촉진하는 소모품 및 다양한 산업용 단백질 시퀀싱 서비스를 제공하는 수탁 연구 기관으로 구성되어 있습니다. 바이오마커 탐색과 의약품 개발에 대한 수요 증대가 이 분야의 기술 혁신을 계속 추진하고 있습니다.
| 주요 시장 통계 | |
|---|---|
| 예측 기간 | 2024-2033년 |
| 평가(2024년) | 18억 3,630만 달러 |
| 예측(2033년) | 26억 9,700만 달러 |
| CAGR | 4.36% |
2023년 당초 17억 4,900만 달러로 평가된 세계의 단백질 시퀀싱 시장은 2033년에는 26억 9,700만 달러에 이르고, CAGR 4.36%로 현저한 성장을 보일 것으로 예측되어 대폭적인 성장이 예상되고 있습니다. 맞춤형 의료가 중시되게 된 것이, 단백질 시퀀싱의 큰 추진력이 되고 있습니다. 단백질의 정확한 아미노산 서열과 수식을 이해하는 것은 바이오마커를 특정하고 암, 신경변성질환, 심혈관질환 등의 질환에 대한 표적요법을 개발하는 데 매우 중요합니다. 단백질 시퀀싱은 창약에서도 필수적이며 단백질 구조에 대한 상세한 지식을 통해 창약 타깃이 될 수 있는 단백질의 동정이 가능해집니다. 바이오의약품 기업은 모노클로날 항체나 치료용 단백질 등의 생물제제 개발에 시퀀스 데이터를 활용하고 있습니다.
기술의 진보로 단백질 시퀀싱의 정확성과 접근성이 계속 향상되고 있는 가운데, 이 시장은 헬스케어 제공에 혁명을 가져오고, 예방 의료와 맞춤형 의료의 시대를 세계 규모로 개척하는 원동력이 되고 있습니다.
이 시장의 제품에는 질량 분석기 및 시퀀싱과 같은 장비, 단백질 준비, 소화, 분석에 필수적인 시약 및 소모품 등이 포함되어 있습니다. 이 도구는 연구자가 정확하고 높은 처리량의 단백질 시퀀싱을 수행하는 데 필수적입니다. 게다가 수탁 연구 기관이나 그 외의 서비스 프로바이더는, 바이오 제약 회사, 학술 기관, 연구소에 프로틴 시퀀스 서비스를 제공하는데 있어서 중요한 역할을 하고 있습니다. 이러한 서비스에는 단백질의 동정부터 복잡한 번역 후 수식의 해석까지 모든 것이 포함됩니다. 바이오마커 탐색, 개별화 의료, 바이오 의약품에 있어서 용도의 확대에 수반해, 단백질 시퀀싱 시장의 제품 및 서비스에 대한 수요는, 특히 북미나 아시아 태평양등의 지역에서 증가하고 있습니다.
본 보고서에서는 세계의 단백질 시퀀싱 시장에 대해 조사했으며, 시장 개요와 함께 제품 및 서비스별, 용도별, 시료 유형별, 투입 시료의 복잡성과 판독의 복잡성별, 기술별, 최종 사용자별, 지역별 동향과 시장 진출기업 프로파일 등의 정보를 제공합니다.
Introduction to Protein Sequencing
Protein sequencing is the process of determining the precise order of amino acids in a protein, which is crucial for understanding its structure, function, and role in biological systems. It plays an essential role in fields such as biotechnology, biomedical research, drug discovery, and disease diagnostics. Protein sequencing provides valuable insights into post-translational modifications, protein interactions, and disease mechanisms, enabling advancements in precision medicine and targeted therapies.
The two primary techniques for protein sequencing are Edman degradation and mass spectrometry. Edman degradation is used for smaller proteins, sequentially removing amino acids, while mass spectrometry is widely used for large-scale proteomics due to its high throughput and ability to analyze complex samples. Additionally, the market consists of instruments, reagents, consumables that facilitate the sequencing process, and contract research organizations providing protein sequencing services for various industries. The growing demand for biomarker discovery and drug development continues to drive innovations in this space.
| KEY MARKET STATISTICS | |
|---|---|
| Forecast Period | 2024 - 2033 |
| 2024 Evaluation | $1,836.3 Million |
| 2033 Forecast | $2,697.0 Million |
| CAGR | 4.36% |
Market Introduction
The global protein sequencing market, initially valued at $1,749.0 million in 2023, is poised for substantial growth, projected to reach $2,697.0 million by 2033, marking a remarkable compound annual growth rate (CAGR) of 4.36%. The growing emphasis on personalized medicine is a major driver for protein sequencing. Understanding the precise amino acid sequence and modifications of proteins is crucial for identifying biomarkers and developing targeted therapies for diseases such as cancer, neurodegenerative disorders, and cardiovascular conditions. Protein sequencing is also essential in drug discovery, where detailed knowledge of protein structures enables the identification of potential drug targets. Biopharmaceutical companies rely on sequencing data to develop biologics, such as monoclonal antibodies and therapeutic proteins.
As advancements in technology continue to enhance the accuracy and accessibility of protein sequencing, the market is primed to revolutionize healthcare delivery, ushering in an era of preventive and personalized medicine on a global scale.
Products in this market include instruments such as mass spectrometers and sequence and reagents and consumables essential for protein preparation, digestion, and analysis. These tools are vital for researchers to conduct precise, high-throughput protein sequencing. Additionally, contract research organizations and other service providers play a crucial role in offering protein sequencing services to biopharmaceutical companies, academic institutions, and research labs. These services encompass everything from protein identification to complex post-translational modification analysis. With growing applications in biomarker discovery, personalized medicine, and biopharmaceuticals, the demand for products and services in the protein sequencing market has been increasing, particularly in regions such as North America and Asia-Pacific.
Industrial Impact
The industrial impact of the protein sequencing market has been profound, significantly influencing various sectors, including healthcare, pharmaceuticals, biotechnology, and research. In the healthcare industry, protein sequencing enables the identification of biomarkers for early disease detection, leading to more precise diagnostics. It supports the development of personalized medicine, allowing for tailored treatments based on a patient's unique protein expression profile. In the manufacturing of biologics, ensuring protein integrity and sequence consistency is critical for maintaining product quality. Protein sequencing is used extensively in process optimization and quality control to monitor the purity and structural fidelity of proteins used in biopharmaceutical production. Moreover, the increasing use of sequencing in academic and clinical research has been driving scientific discoveries and expanding one's understanding of diseases and human biology. Overall, the integration of protein sequencing across these industries has fostered innovation, improved efficiency, and opened new avenues for economic growth and development. The integration of novel sequencing technologies and mass spectrometry has enhanced the scalability and precision of protein sequencing, increasing its industrial application across multiple sectors.
Market Segmentation
Segmentation 1: By Product and Service
Product Segment to Lead the Global Protein Sequencing Market (by Product and Service)
In the global protein sequencing market, as of 2023, the product segment held the largest share at 72.37%. This dominance can be attributed to the essential role of products such as mass spectrometry instruments and sample preparation reagents in the sequencing process.
Segmentation 2: By Application
Biotherapeutics to Witness the Highest Growth between 2024 and 2033
Based on application, the global protein market was led by the biotherapeutics segment, which held a 69.51% share in 2023. Protein sequencing is crucial in developing and manufacturing biotherapeutics, including monoclonal antibodies, therapeutic proteins, and vaccines. Sequencing is essential for understanding protein structure, ensuring safety and efficacy, and optimizing manufacturing processes. This application area has been witnessing significant growth due to the rise of precision medicine and the increasing demand for targeted therapies in chronic diseases such as cancer, autoimmune disorders, and genetic conditions. The global burden of chronic diseases, particularly cancer, diabetes, and autoimmune diseases, has been pushing the demand for biotherapeutics, where protein sequencing plays a key role in the discovery and development of novel treatments.
Segmentation 3: By Sample Type
Biological Samples Segment to Witness the Highest Growth between 2024 and 2033
Biological samples, which include a wide range of samples from living organisms (such as blood, urine, and saliva), are essential for various applications, including clinical diagnostics, drug development, and personalized medicine. The increasing demand for targeted therapies and personalized healthcare has been driving the growth of this segment. The development of advanced protein sequencing technologies, such as mass spectrometry and next-generation protein sequencing (NGS), has made it easier and more cost-effective to analyze biological samples in the near future.
Segmentation 4: By Technology
Mass Spectrometry Segment to Occupy the Major Market Share between 2024 and 2033
In the protein sequencing market, the mass spectrometry segment will occupy the major market share between 2024 and 2033. Nevertheless, as next-generation sequencing technologies become more established and integrated into research workflows, they will shift market dynamics. Nanopore sequencing enables real-time sequencing of proteins and is particularly appealing due to its ability to provide long-read sequencing capabilities. Although still emerging, nanopore technology will enhance protein sequencing by providing insights into protein structure and interactions that mass spectrometry may not fully capture. This will also lead to increased collaboration and the development of hybrid approaches that leverage the strengths of both sequencing and mass spectrometry.
Segmentation 5: By End User
Academic Institutes Segment to Hold the Major Market Share between 2024 and 2033
In the global protein sequencing market, as of 2023, the academic institute segment held the largest share at 47.30%. The growth of the protein sequencing market has been fueled by rising investments in proteomics research. For example, Thermo Fisher's Quantitative Proteomics Research Grant Program provides up to $11,000 in mass spectrometry reagents to doctoral and post-doctoral students, promoting innovative research in quantitative proteomics. This initiative highlights private-sector support for academic research. Moreover, collaborations between academic institutions and biotech companies have been driving technological advancements, enhancing research capabilities, and broadening the market.
Segmentation 6: By Region
The protein sequencing market in the North America region is expected to witness a significant growth rate of 3.81% during the forecast period, marked by the increasing demand for preventative medicine, clinical diagnostics, drug development, and biomarker discovery. However, the Asia-Pacific region is expected to reach $623.5 million in 2033 from $348.4 million in 2023, at a CAGR of 5.93% during the forecast period 2024-2033.
Recent Developments in the Protein Sequencing Market
Demand - Drivers, Challenges, and Opportunities
Market Demand Drivers:
Advancements in Computational Biology and Bioinformatics: Recent advancements in computational biology and bioinformatics have significantly influenced the protein sequencing market, particularly in drug discovery, proteomics research, and biomarker identification. These technologies utilize sophisticated algorithms, simulations, and extensive biological datasets to improve the design and analysis of protein sequences, thereby enhancing the accuracy and efficiency of sequencing methods.
Market Challenges:
Shortage of Skilled Labor: The protein sequencing process entails complex procedures that require a comprehensive understanding of biochemistry, molecular biology, and advanced analytical techniques. Skilled professionals are essential to operate sophisticated instruments, such as mass spectrometers, to ensure accurate and reliable data acquisition. Moreover, these experts must possess strong computational and bioinformatics capabilities to manage and interpret the substantial volumes of data generated during sequencing.
Market Opportunities:
Integration of Artificial Intelligence: The integration of artificial intelligence, particularly machine learning algorithms such as XGBoost, with protein sequencing technologies presents a significant opportunity to transform the field of molecular diagnostics and therapeutic decision-making. By employing novel materials, such as solid-state 2D phosphorene nanoslit devices, AI-enhanced models can significantly improve the accuracy and speed of amino acid identification at the single-molecule level, addressing long-standing challenges in high-throughput protein sequencing.
How can this report add value to an organization?
Product/Innovation Strategy: The report offers in-depth insights into the latest technological advancements and emerging applications in protein sequencing, enabling organizations to drive innovation and develop cutting-edge products tailored to market needs.
Growth/Marketing Strategy: By providing comprehensive market analysis and identifying key growth opportunities, the report equips organizations with the knowledge to craft targeted marketing strategies and expand their market presence effectively.
Competitive Strategy: The report includes a thorough competitive landscape analysis, helping organizations understand their competitors' strengths and weaknesses and allowing them to strategize effectively to gain a competitive edge in the market.
Methodology
Key Considerations and Assumptions in Market Engineering and Validation
Primary Research:
The primary sources involve industry experts in protein, including the market players offering products and services. Resources such as CEOs, vice presidents, marketing directors, and technology and innovation directors have been interviewed to obtain and verify both qualitative and quantitative aspects of this research study.
The key data points taken from the primary sources include:
Secondary Research
Open Sources
The key data points taken from the secondary sources include:
Key Market Players and Competition Synopsis
Profiled companies have been selected based on inputs gathered from primary experts, as well as analyzing company coverage, product portfolio, and market penetration.
The global protein sequencing market is driven by a diverse group of key players, each leveraging advanced technologies to meet the growing demand for accurate, high-throughput protein analysis. Some of the key players, including Thermo Fisher Scientific Inc., Agilent Technologies Inc., Bio-Rad Laboratories provide cutting-edge sequencing platforms, reagents and software. Further, the market also includes the presence of various service providers, such as Charles River Laboratories International, Inc. and Creative Proteomics, which have established a competitive advantage by offering tailored protein sequencing solutions, ranging from protein characterization to post-translational modifications.
Some prominent names established in this market are:
Scope and Definition